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If a person doesn't have CD4 on T-Helper. Would this person be susceptible to HIV infection?


Suppose there is an individual who carries a mutation such that the surface of that person's T-helper lymphocytes and macropahges only do not carry the CD4 marker. Would this person be susceptible to HIV infection? What about the secondary infections characteristic of AIDS?

i dont think there is any healthy person who doesnt have the CD4, if you were lacking this you would probably be long dead from the flu or something.
in theory though, u would more readily go from HIV+ to full blown AIDS if u already had a depleted level of CD4 cells.
again, i have never heard of a healthy person (one not infected with HIV) who has a lowered CD4 count, or no CD4 cells at all...i would imagine that u cant live without them. hence people with HIV/AIDS die when their CD4 cells are completely depleted.

all of us are susceptible to HIV

no, they wouldn't, however, their t cells wouldn't be able to function anyhow, because the cd4 molecule is a vital component of it's immune functions. therefore, you'd still have health like an hiv carrier.

Most people are suseptible to HIV but you have to come into contact with an infected persons body fluids/blood to contract it. I suggest always use condoms.

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