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If both parents contain a genetic variant for HIV, whats the probability that offspring will develop AIDS? |
Only those knowledgeable in the topic answer, please. Youre right, I probably should have clarified. HIV is not passed down (in a hereditary sense) from the parents. The only significant possibility is if the mother is infected with HIV and not keeping her viral load under control with meds. Even then, the likelihood that the fetus will contract HIV during gestation or birth is relatively small (10-20%; if the mom's viral load is under good control, the risk is only about 1%) because, as a general rule, the mother's blood doesn't mix with the fetus' blood (unless something is wrong). It's also possible that the newborn will contract HIV from the mother during breastfeeding (although the chances are relatively low if the mother is taking antiviral meds). Sometimes a newborn will be given a course of antivirals (or a single shot) as a *prophylaxis* if the mother was HIV+ and under poor control, but this is controversial and not generally done in the developed world. |
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